Propanamide, N-(2-cyano-5-formyl-3-pyridinyl)-2,2-dimethyl-
N-(2-Cyano-5-formylpyridin-3-yl)pivalamide
CAS: 1246088-39-0
Molecular Formula: C12H13N3O2
Propanamide, N-(2-cyano-5-formyl-3-pyridinyl)-2,2-dimethyl- - Names and Identifiers
| Name | N-(2-Cyano-5-formylpyridin-3-yl)pivalamide |
| Synonyms | N-(2-Cyano-5-formylpyridin-3-yl)pivalamide Propanamide, N-(2-cyano-5-formyl-3-pyridinyl)-2,2-dimethyl- |
| CAS | 1246088-39-0 |
Propanamide, N-(2-cyano-5-formyl-3-pyridinyl)-2,2-dimethyl- - Physico-chemical Properties
| Molecular Formula | C12H13N3O2 |
| Molar Mass | 231.25 |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD17171317 |
Propanamide, N-(2-cyano-5-formyl-3-pyridinyl)-2,2-dimethyl- - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Hazard Class | IRRITANT |
Propanamide, N-(2-cyano-5-formyl-3-pyridinyl)-2,2-dimethyl- - Introduction
N-pivalamide is an organic compound with the chemical formula C12H14N2O2. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: N-pivalamide is a yellow to orange solid.
-Solubility: Soluble in some organic solvents, such as methanol, chloroform, etc.
-Melting point: about 84-87°C.
-Density: about 1.2g/cm³.
Use:
N-(pivalamide) is an intermediate compound commonly used in organic synthesis. It can be used to synthesize biologically active compounds, such as drugs, pesticides, etc. The specific scope of application is determined by the synthesis target.
Preparation Method:
The preparation method of N-(Br) pivalamide can be carried out by the following steps:
1. Condensation reaction of 2 cyano-5-chloropyridine -3-formaldehyde with amino propionic acid to generate N-(chloropyridine) pivalamide.
2. Subsequently, N-(-) pivalamide is reacted with a base, such as triethylamine, to remove chlorine to obtain the final product N-(-) pivalamide.
Safety Information:
Information on the specific toxicity and safety of N-(a) pivalamide is limited, so general laboratory safety practices should be followed when handling and storing the compound. Personal protective equipment such as laboratory safety glasses and gloves should be worn during use. Before handling the compound, it is best to conduct a toxicological assessment and ensure that the experimental site is well ventilated. In the event of accidental exposure to this compound, rinse immediately with plenty of water and seek medical advice.
Nature:
-Appearance: N-pivalamide is a yellow to orange solid.
-Solubility: Soluble in some organic solvents, such as methanol, chloroform, etc.
-Melting point: about 84-87°C.
-Density: about 1.2g/cm³.
Use:
N-(pivalamide) is an intermediate compound commonly used in organic synthesis. It can be used to synthesize biologically active compounds, such as drugs, pesticides, etc. The specific scope of application is determined by the synthesis target.
Preparation Method:
The preparation method of N-(Br) pivalamide can be carried out by the following steps:
1. Condensation reaction of 2 cyano-5-chloropyridine -3-formaldehyde with amino propionic acid to generate N-(chloropyridine) pivalamide.
2. Subsequently, N-(-) pivalamide is reacted with a base, such as triethylamine, to remove chlorine to obtain the final product N-(-) pivalamide.
Safety Information:
Information on the specific toxicity and safety of N-(a) pivalamide is limited, so general laboratory safety practices should be followed when handling and storing the compound. Personal protective equipment such as laboratory safety glasses and gloves should be worn during use. Before handling the compound, it is best to conduct a toxicological assessment and ensure that the experimental site is well ventilated. In the event of accidental exposure to this compound, rinse immediately with plenty of water and seek medical advice.
Last Update：2024-04-09 21:32:53
